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Rehab News:Gene therapy 'could one day help alcoholics'

One leading expert on addiction medicine is suggesting that gene therapy could be the key to understanding why some people are prone to alcohol dependence.

Professor Charles O'Brien from the University of Pennsylvania has pointed out that numerous recent studies illustrate how vulnerability to substance abuse appears to run in families.

"If you are unlucky enough to be born with a gene that predisposes you to addiction, you are likely to have problems if you dabble with drugs," Dr O'Brien explained to the Dominion Post. "Whereas other people might indulge in the same sort of risky impulsive behaviour but not become addicted."

Dr O'Brien's belief that addiction could potentially be a chronic disorder has already revolutionised treatment science, but many scientists and councillors insist that it should still be treated as a moral failing and that it can be cured solely through therapy and willpower.

His hope is that a genetic treatment programme - if successful - could help bring about a shift in public opinion, but he admits developing one will be an uphill struggle.

"Genes are switched on and off by environmental factors," he explained. "Ten years ago we thought there were three or four major genes involved in alcoholism - now we think there are 300-400."